The phrase "a substantial handling" is correct and usable in written English.
It can be used when referring to a significant amount of management, treatment, or processing of something, often in a business or logistical context.
Example: "The project required a substantial handling of resources to ensure its success."
Alternatives: "a considerable management" or "a significant processing".
This behaviour is a dramatic example of how dolphins, with their relatively unspecialised morphology, can utilise behavioural flexibility to tackle prey items that require substantial handling before consumption.
The preparation process, however, involves substantial handling of large amounts of potentially contaminated product, and the risk for exposure of infants to this process is high.
Toward the end of his 50-minute opening statement, the chief prosecutor, Steven C. Lember, told the jury that the chauffeur, Costas Christofi, was killed because Mr. Williams had shown "a conscious disregard of a substantial risk" while handling a double-barreled, 12-gauge shotgun as Mr. Christofi walked just feet away.
In addition, even after a fish is successfully grasped, there is a substantial difference in handling time depending on the capture point (Figure 9).
Away from home, handling a substantial amount of money for the first time (his student loan), he went to a casino for the first time with some of his new friends.
He contributes a substantial amount of time handling Legal Aid Society cases for poor people being prosecuted on vice, drug and other criminal charges.
Whatever the exact answer, there is some support for the view that schools can handle a substantial fraction of poor students without sacrificing performance.
The standard errors in Table 2 adjust for correlation among applications to the same ad by clustering on ads; this handles a substantial share of the likely error correlations in our data since the typical ad received about 63 applications.
A total of 356 samples were randomly collected between 2002 and 2004 from 356 patients at the Tri-Service Generalargepital, a large medical center that handles a substantial number of TB patients referred from hospitals throughout Taipei.
Sonication of a large explanted prosthesis is, however, technically demanding and carries a substantial risk of contamination during handling (Trampuz et al. 2006).
