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CHC production has a substantial genetic component and therefore varies within genetically diverse colonies [20], [23], and ants exchange CHCs by trophallaxis [18], [31].
Like other diseases, addiction has a substantial genetic component.
ASD has a substantial genetic component, with 88-95% trait concordance among monozygotic twins.
Do, C.B. et al. Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
Despite evidence of a substantial genetic component, the genetic factors that underlie longevity in humans remain to be identified.
Human twin studies have suggested that there is a substantial genetic component underlying nicotine dependence, ongoing smoking and ability to quit.
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All the LDD traits displayed a significant and substantial genetic component, with heritability estimates of 37.7% ± 4.48% (disc signal intensity) to 58.0% ± 5.34% (disc height).
Therefore, we need to be aware that some of the effects of family characteristics that are described in the following will have some (maybe substantial) genetic component, and that some genetic effects remain unobserved.
Large-scale association studies will be essential in the quest to identify variants that make up the substantial genetic component implicated by quantitative genetic studies.
The substantial genetic component in LBP1 observed in variance component analysis is confirmed by concordance rates differing between the monozygotic and dizygotic twins (tetrachoric correlation in monozygotic vs dizygotic twins 0.641 vs 0.375, p=0.018) and by multiple logistic regression analysis (table 3).
Gut inflammatory diseases such as IBD have been long known as having a substantial genetic predisposition component and a recent review of genome-wide scans reported on the seven confirmed and replicated cases of genetic susceptibility loci, with many more, however, that need independent confirmation and verification [42].
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