As a critical cytokine, TNF can induce a wide range of intracellular signaling pathways, and a substantial part of its function is primarily mediated by the MAPK cascade.
The overlap in gene expression profiles between fasting and incubation with WY14,643 shows that PPARα in PBMCs carries out a substantial part of its function during fasting, when concentrations of its natural ligands, free fatty acids, are elevated in the blood.
These quality management standards are often institutionalized, which means firms only adopt certain quality management standards ceremoniously without any substantial function and practice.
Ranking functions play a substantial role in the performance of information retrieval (IR) systems and search engines.
Some patients did recover substantial function and it allowed them to do things they couldn't do for years, but others did not".
The proportions of the subsystems may be changed, but no substantial function has been added or left out.
The use of soft elastic biomaterials in medical devices enables substantial function integration.
After accounting for redundant probes that targeted identical genes and removing probes targeting hypothetical proteins without substantial function or ontology information, significant annotation and network information was available for 90 genes orthologous to human genes with established functions.
Fortunately, it would appear from the activity-assay results that the C. cellulolyticum cohesin module (in combination with its matching dockerin) may retain atleast a substantial fraction of its function throughout the course of the 78-h assay.
This suggests that factors such as parenting quality, stress, family composition, overcrowding, residential mobility, racism and family functioning have a substantial mediating role in the pathway from material wellbeing to poor mental health.
