The phrase "a substantial focus for" is correct and usable in written English.
It can be used when discussing the main area of attention or concentration in a particular context, such as research, projects, or discussions.
Example: "The study has a substantial focus for understanding the impact of climate change on biodiversity."
Alternatives: "a significant emphasis on" or "a major concentration for".
As we have already made clear, mental health remains a substantial focus for our investigation".
The Metropolitan police commissioner, Sir Bernard Hogan-Howe, said: "Mental health remains a substantial focus for our investigation".
There is a substantial focus for small and big business to be aware of curation as a marketing tactic to grow user conversion on social media and websites.
Consequently, tyrosine kinases have been a substantial focus for the development of targeted therapeutics.
That's a real focus for us.
Among the various polymeric architectures, dendritic polymers have received a substantial scientific focus for their highly branched, multifunctional, and well-defined structures.
This fact, in and of itself, provides evidence for the substantial focus that must take place in hospital on discharge planning for those at the end of life.
This may not be the clear-cut biggest Big Data application (Google's revenue was $66 billion last year, for example), but it's substantial, focused and paid for by the public.
There have been a substantial research focusing on the interference mitigation through power control.
Because of the gaps in scientific knowledge, the high prevalence of M. tuberculosis infection among elephants living in North America, and the insensitivity of diagnostic tests, a substantial need exists for focusing attention on infection control practices and occupational health programs specifically designed to reduce zoonotic M. tuberculosis transmission in the captive elephant industry.
When Netscape refused to abandon its efforts to develop Navigator into a substantial platform for applications development, Microsoft focused its efforts on minimizing the extent to which developers would avail themselves of interfaces exposed by that nascent platform.
