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Growing skin required scientific ingenuity, but the oesophagus also presents a substantial engineering challenge.
A substantial engineering sector serves the needs of the mining industry.
Here the route crosses the Sioux Narrows Bridge, the last part of the highway to be constructed and a formidable engineering obstacle in the 1930s.
What is in between doesn't really matter except as a vector, a set of engineering obstacles to be overcome.
Those who favor military action are again making the threat appear closer than it is by minimizing the substantial technological and engineering obstacles that Iran must overcome to be able to enrich uranium and manufacture a weapon.
"We see fusion as a series of very substantial engineering challenges," says the company's chief executive David Kingham.
However, immune rejection is a substantial obstacle to implantation of genetically engineered allogeneic or xenogeneic cells.
He contends that the joint opinion's "undue burden" standard requires the application of strict scrutiny to "all non de minimis" abortion regulations, ante, at 5, but that could only be true if a "substantial obstacle," ante, at 34 (joint opinion), were the same thing as a non de minimis obstacle--which it plainly is not.
showing on the record before us" that these requirements constitute a "substantial obstacle" to abortion decisions.
As the judge rightly said, this provision constitutes "a substantial obstacle in the path of a woman seeking an abortion".
However, the long start-up period remains a substantial obstacle in the stable operation of the UASB reactor.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com