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Most commercially available hemofilters do not permit a substantial elimination of cytokines because of the low cut-off point of their membranes.
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The response of the current paper is to include new data with a FRET pair having a longer Rzero, showing more substantial elimination of FRET due to the GPGP insertion, for which the small but possibly detectable FRET change in the previous experiments with the shorter Rzero dye pair.
These dialysers are characterized by a larger pore size, which allows enhanced middle molecule removal without substantial elimination of albumin [ 15].
Recently, Sri Lanka has achieved a significant reduction in malaria incidence since 2000 and embarked on a malaria elimination phase in 2009 of a substantial progress toward elimination of malaria in the last decade [ 8].
Indeed, renal clearance represents a substantial contribution to topotecan elimination, and cisplatin disposition is dominated by near covalent binding of the drug to serum proteins.
A substantial reduction in the elimination time occurs for WPV3 in the scenarios we explored for Bihar (top of Table 3) but not for WUP (bottom of Table 3) even in the case of SIAs expanded to all ages.
If sulfates are unrelated to mortality, as some have argued (Grahame and Schlesinger 2005), the elimination of a substantial fraction of nontoxic material from PM2.5 mass should result in a substantial increase in the PM2.5 coefficient, which would otherwise have been suppressed by the large fraction of mass that was nontoxic.
Colugnati et al. predicted that a vaccination against CMV would not need to have high efficacy nor wide-spread coverage to make a substantial impact on CMV transmission and elimination of CMV from the population has the potential to greatly reduce the incidence of disease attributable to CMV infection [6], [80].
It is not known whether the inactivation of PanK2 results in decreased cellular CoA in human neurons, but the significant effects of PanK1 inactivation in the liver suggest that the elimination of PanK2, a substantial isoform in brain, would have similar consequences for neuronal CoA homeostasis.
Certainly there would be a substantial health cost savings due to elimination of resources dedicated to monitoring, dosing and prescription of warfarin anticoagulation.
Active feedback dilution of ferrocene-based catalyst vapor leads to an almost complete elimination of SWCNT bundling and a substantial increase in SWCNT lengths via the suppression of bundling-induced growth termination.
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