The phrase "a substantial elevation" is correct and usable in written English.
It can be used when describing a significant increase in height, level, or amount in various contexts, such as geography, architecture, or even metaphorically in discussions about status or quality.
Example: "The new building features a substantial elevation that offers stunning views of the city skyline."
Alternatives: "a significant increase" or "a considerable rise."
These records are substantially more coastal than most G. severnsi collections, but also at a substantial elevation compared to other records of the species.
The eastern side of the island, the body of the tadpole, is an ancient barrier island with a substantial elevation and large dunes, supporting a maritime forest and a major bird sanctuary.
There is a substantial elevation of these risks in migraineurs using CHC [11-14] [11-14]
There is a substantial elevation of these risks in migraineurs using combined contraceptive pills (COC).
Our analysis revealed a substantial elevation in substitution rate for rrn5 in S. latifolia.
After 4 weeks of CCl4 intoxication, severe hepatic fibrosis accompanied by a substantial elevation in serum ALT and AST levels was induced.
The effect of removing the morbidity study (Yamada et al. 2004) from the analysis [see Supplemental Material, Table S4 (http://dx.doi.org/10.1289/ehp.1204982)] is generally to slightly increase risks; there is a more substantial elevation for circulatory disease apart from heart disease and CVA, but this contributes relatively modestly (6 25%) to overall circulatory disease mortality (Table 3).
PROGRESS (the Perindopril Protection against Recurrent Stroke Study) showed lowering of blood pressure in patients with substantial elevation using an ACE inhibitor and diuretic reduced the risk of recurrent stroke.
A previous study has demonstrated that substantial elevation of AP endo activity, as well as APE/ Ref-1 levels, is characteristic of adult gliomas [ 38].
However, the observation that some individuals with HNF1A-MODY had hs-CRP levels >10 mg/l (including one of 52 mg/l) demonstrates that HNF1A haploinsufficiency is not sufficient to prevent substantial elevation in CRP levels, presumably as part of an acute inflammatory response.
Mark McKinnon, the media strategist who twice helped George W. Bush win the presidency, said that voters might have soured on President Obama by 2012 -- might be "tired of a president known for his confidence, lofty oratory, urbane repose, hip fashion, full head of hair and substantial elevation".
