Sentence examples for a substantial effort has from inspiring English sources

Owing to the outstanding service life of metallic prostheses, a substantial effort has been put into their surface modification to improve biocompatibility and reduce metallic ion diffusion.

Since the advent of AOP in 1997, a substantial effort has been invested in discovering how such abstractions can enhance reuse methodologies such as frameworks (Fayad and Schmidt 1997) and product lines (Clements and Northrop 2002).

A substantial effort has been put forth to investigate any promising cardioprotective strategy to effectively reduce myocardial infarct size.

Worldwide, a substantial effort has been made resulting in the collection of a large amount of data aimed at the identification of QTLs [ 10- 15].

During the past 20 years, a substantial effort has been made by CDC, WHO, PAHO, and private and public partners working with governments to provide existing vaccines in an equitable manner to some of the world's most disadvantaged populations, and to ensure that these populations have equal opportunities to receive new vaccines, such as rotavirus and pneumococcal vaccines (9, 10 ).

No respondent in any jurisdiction reported any substantial effort having been made to recruit Indigenous staff or to seek out a suitable Indigenous person for the Board.

Because LT plays a key role in virulence during anthrax infections, substantial effort has been directed to the development of vaccines and therapeutics that target this toxin.

In recent years, substantial effort has been directed toward an understanding of strain-specific pathogenicity and transmission behavior in G. salaris (reviewed in Bakke et al. 2007).

Substantial effort has been devoted to creating a health care environment in which the needs and preferences of patients are both acknowledged and incorporated into decision-making.

Since 2003, substantial effort has been directed toward the development of a DNA-based identification system for animal life, based upon the analysis of sequence diversity in the 5' region of the mitochondrial gene, cytochrome c oxidase 1 [ 1, 2].

Substantial effort has been dedicated to determining whether age is a primary determinant of ICU outcome for very old patients [ 6- 9, 11, 13- 15, 20, 29, 36- 39].