The phrase "a substantial effect in" is correct and usable in written English.
It can be used when discussing the impact or influence of something in a particular context or area.
Example: "The new policy is expected to have a substantial effect in improving employee productivity."
Alternatives: "a significant impact on" or "a considerable influence in".
Meyersson: Industrial espionage had quite a substantial effect in East Germany.
In the latest twist, a review of more than 700 studies has concluded that echinacea has a substantial effect in preventing colds and in limiting their duration.
This new research shows that even cues that are not directly related to an individual's goal can have a substantial effect in a task environment, influencing cognition and the subsequent manner in which the task is completed.
An American investor could bring suit against a foreign company in connection with an investment if there was sufficient conduct by the foreign company in the United States and it had a substantial effect in the United States or on its citizens.
However, RF impairments and real-life propagation conditions can have a substantial effect in the actual gains observed in practical cases.
Most of these exhibit little sensitivity, and substantial changes in these parameters barely influence predictions likely to influence forest management – but two of these parameters have a substantial effect in the longer term: the magnitude of the swindle and the duration of serial correlation.
Therefore, one may argue that these EQ-5D dimensions may not have a substantial effect on HRQOL in patients with SP. Problems in mobility may not refer to SP but rather to other co-morbidities.
Second, we found a substantial effect of radiotherapy in terms of absolute risk reduction in older women, but less so in younger women in the last update of SweDCIS (Holmberg et al, 2008).
TOF showed the highest SUVmax deviations in low-contrast lesions, whereas PSF revealed a substantial effect on SUVmax in high-contrast lesions.
This work demonstrates a means of GIW simulation with improved spatial detail while showing that GIWs, in-aggregate, have a substantial effect on downstream hydrology in the studied watershed.
Supplemental food programs have a substantial effect on nutrition in pregnancy and limit weight gain for older children and adults.
