The phrase "a substantial difference from" is correct and usable in written English.
It can be used when comparing two things to highlight a significant distinction between them.
Example: "There is a substantial difference from the previous model in terms of performance and efficiency."
Alternatives: "a significant difference from" or "a marked difference from".
The potential difficulty of their job became clear after Vice President Joseph R. Biden Jr., following an evening meeting with Senate Democrats, said negotiators had effectively settled on $33 billion in reductions from current spending, a substantial difference from the $61 billion endorsed by the House in February.
The bistatic case shows a substantial difference from the traditional monostatic case.
So, the morphology of G-Ag2S composites has a substantial difference from that of the Go sheet.
For some examples we executed 5-fold cross-validation and 5-fold nested cross-validation (results not shown), but did not observe a substantial difference from 10-fold.
For if we agree that there is no actual time travel in our universe, the supposition that there might have been involves postulating a substantial difference from actuality, a difference unlike in kind from anything we could know if firsthand.
This is a substantial difference from the parental ΔsecA2 single mutant, which is known to be only moderately attenuated for growth in mice and most likely persists at least at low levels for many weeks and perhaps permanently [21].
Cluster G is a cluster with predominant specificity to ∼14, 30, 26, and 38 kDa proteins (again, a substantial difference in representation from each exposure group, where the greatest percentage was from the bitten but not infected group).
Cluster F is a cluster with antibodies specific almost exclusively to the ∼38 kDa salivary protein (a substantial difference in representation from each exposure group, where the greatest percentage of individuals was from the Leishmania-infected group).
A large thermomagnetic effect implies a substantial difference between heat supply from depth and surface and/or near-surface heat discharge.
In this paper we focus on the question of a substantial difference between SAMs derived from either alkylthiols or disulfides using cyclic voltammetry.
A substantial difference in the time from ICU admission to enrollment was observed between studies.
