Sentence examples for a substantial delay of from inspiring English sources

There has not been a substantial delay of other Grand Theft Auto games in the past, said a company spokesman, Edward Nebb.

She finds a substantial delay of motherhood of approximately 1.5 2 years.

In a between-subjects design, we observe the impact of a substantial delay of risk resolution (2 days) on investment choices.

Control strategies that reduce the spread of the disease during the early phase of a pandemic wave may lead to a substantial delay of the epidemic.

30 While early stages of fertility reduction would be associated with a decreased number of children per woman without a substantial delay of motherhood, later stages of fertility reduction appear to be primarily associated with delayed motherhood.

Industry representatives advanced alternative explanations and used the early diversity of scientific opinions for its legal argument that toxicity was not the responsibility of industry, nor could it have been anticipated, thereby causing a substantial delay of remediation, compensation, and prevention.

The empirical evaluation indicates that hybrid analysis may be useful to derive more up-to-date estimates of long-term survival compared with traditional design options if there is a strong improvement of survival over time, even in situations with a substantial delay in recording of incident cases.

Our experiments disclose the absence of physical interaction between Grk6 to the activated mutant receptor, a substantial delay in recruitment of β-Arrestin 2 to the activated mutant receptor, and a delay in receptor internalization, trafficking and Erk1/2 activation induced by the ligand.

ICR16 and ICR62 were poor inhibitors of the growth in vitro of the vulval carcinoma A431, but both induced a substantial delay in the growth of xenografts of this tumour and 4/8 tumours regressed completely in the mice treated with ICR62 (total dose 2.2 mg).

This can lead to a substantial delay in reperfusion of the myocardium at risk [ 2].

As expected, the observed defect in sporozoite locomotion and invasion to mosquito salivary glands translates into a substantial delay or absence of infection during natural transmission.