The phrase "a substantial decrease in the number" is correct and usable in written English.
You can use it when discussing a significant reduction in quantity or figures, often in contexts like statistics, reports, or analyses.
Example: "The recent study showed a substantial decrease in the number of participants compared to last year."
Alternatives: "a significant drop in the number" or "a considerable reduction in the number."
Malformations in the PMBSF resulted in a substantial decrease in the number of barrels as identified by cytochrome oxidase activity.
When the deal was struck, Team Phoenix explained that they expected a substantial decrease in the number of roadside bombs on his stretch of road.
I suspect that if physicians were salaried there would be a substantial decrease in the number of medical procedures performed, including colonoscopies.
We found a substantial decrease in the number of immature neurons and radial glial progenitor cells in the ventral hippocampus of both transgenic models compared with wild-type controls.
RONALD J. VENDER President American College of Gastroenterology New Haven, June 2, 2013 To the Editor: I suspect that if physicians were salaried there would be a substantial decrease in the number of medical procedures performed, including colonoscopies.
In Northern Europe, human activities have caused a substantial decrease in the number of old deciduous trees over the last two centuries, leading to a decline in species populations associated with this habitat.
In addition, ZD6474 treatment in siRNA-induced Atg7 knockdown cells led to a substantial decrease in the total number of surviving cells, when compared with siRNA controls.
There was a substantial decrease in the total number of γ-foci in mouse cell cultures grown for 48 hours in medium including tempol with antioxidant tempol (OX)).
22 In that study, 35 patients with mostly type 3 VWD, prophylaxis was associated with a substantial decrease in the annual number of bleeding events.
A 2011 survey found that only 9percentt of Wikipedia editors identified as female, and a 2012 paper in American Behavioral Scientist, a peer-reviewed academic journal, found that the number of active Wikipedia editors dropped from around 50,000 in 2006 to about 35,000 in 2011, resulting in a substantial decrease in the quality of Wikipedia articles.
