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Using an antibody recognizing the N-terminal region of BRCA1, we found that UVC induced a substantial decrease in levels of this protein at 3 hrs post-treatment, which became more marked by 6 hrs (Fig. 1A, top panel).
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From the present investigation, it is evident that silencing of MIPS can yield major perturbation in the phytic acid biosynthetic pathway leading to substantial decrease in levels of phytate along with an increase in the amount of Pi content.
"We are confident that such efforts will result in a substantial decrease in the level of unrest," the memo says, "but we must also stress that confidence-building measures cannot be held hostage to an unattainable and unnecessary standard.
Short-term results in 12 patients have demonstrated satisfactory outcomes as a salvage procedure with improved function and a substantial decrease in the level of pain.
Our results reveal a substantial decrease in the level of all ErbB family members analyzed after treatment with B-10.
As demonstrated in Figure 3C, we observed a substantial decrease in the level of nascent transcription for TAF7, PTB, and SELENBP1 genes in Drosha-knocked-down cells.
The A673T mutation causes a substantial decrease in the level of the soluble APP fragment processed by β-secretase (sAPPβ) [ 9, 18].
The presence of pGEMT: rnc plasmid that harbors Cj-RNase III in both parental and mutant strains, causes a substantial decrease in PNPase levels due to the presence of higher levels of this protein.
Consistent with previous observation [10], when Aurora-A was co-expressed with different amounts of Cdh1 in HEK293T cells, the increase in the protein level of Cdh1 was accompanied by a substantial decrease in the expression levels of Aurora-A.
PW11 at concentrations >1 mM resulted in a substantial decrease in GM1 levels, whereas WO4 did not affect GM1 levels.
Outdoor sources of benzene are mainly from vehicle traffic, and reductions of benzene in gasoline have contributed to a substantial decrease in benzene levels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com