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The phrase "a substantial criterion" is correct and usable in written English.
It can be used when discussing an important standard or principle that is used to judge or evaluate something.
Example: "In assessing the effectiveness of the program, a substantial criterion is the improvement in participant outcomes."
Alternatives: "a significant standard" or "an important measure".
Exact(2)
A substantial criterion for the efficient use of this wood harvesting combination is the accumulation of wood in the cable corridor.
Interestingly, such a dynamic, diet induced change of UMH excretion may serve in future as a substantial criterion to identify patients with GMA and to differentiate such patients from above mentioned disease conditions with persistently enhanced UMH excretion [ 14, 16].
Similar(58)
Analogous properties of (what on substantial criteria is) slash logic are discussed in Sandu (2007) and Mann et al. (2011); recall Hodges's distinction between independence friendly logic and slash logic (see the beginning of Sect. 3).
As revealed in Table 3, when ventilatory support is not a mandated criterion, a substantial number of patients are included, representing 15-42% of the total population of potential ARDS patients.
The choice of antigens targeted for amplification was based on the several criteria: a) Substantial regions of the target gene had to be amenable to PCR amplification using our primer design strategy, b) Antigen expression should not adversely affect dendritic cell function and c) Antigens had to induce functional CTLs [16] [21].
Even when patients are selected according to the above criteria, a substantial minority of patients will still fail and require intubation, ranging from 7%to30%0% among the controlled trials [ 1].
With this survey, there is a substantial trade-off between criteria for proximity of monitors and the sample size and composition of the available data (Parker et al. 2008a, 2008b).
More patients will meet these criteria than the modified New York criteria, of whom a substantial proportion fail to meet the modified New York criteria at follow-up [51].
Patients above each criterion had a substantial observed improvement in PFS on the PCF20 arm, while only a modest effect was observed below the criterion.
On the basis of a substantial proficiency level model, a criterion for passing learning goals could be provided.
This criterion predicts a substantial number of novel responsive genes, when applied to genomic regions 10 kb upstream of genes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com