The phrase "a substantial cost associated" is correct and usable in written English.
It can be used when discussing expenses or financial implications related to a specific action, project, or decision.
Example: "There is a substantial cost associated with implementing the new software system that we need to consider."
Alternatives: "a significant expense linked" or "a considerable cost tied".
The substantial cost associated with replacing experienced managers calls attention to the need to address job strain in order to retain this valuable organizational asset.
In order to overcome disadvantages of the substantial cost associated with the tungsten carbide (WC) anvil used for large scale commercial production of gem quality large single crystal diamonds, we have developed a modeling of effective design of WC anvil by finite element method (FEM).
With the substantial cost associated with producing clinical registries such as APPROACH, and the commonly associated challenge of missing clinical registry data, our data merging method and translation to ICD-10 can be of value to other researchers.
The substantial cost associated with the average induced abortion in Uganda, reinforces the case made by other researchers--that efforts to reduce unsafe abortions by increasing contraceptive coverage or providing safe, legal abortions, are critical.
Given the substantial cost associated with the maintenance of authoritative health information sites, the paper proposes a more collaborative development in which users can be engaged in the definition of content to ensure relevance and responsiveness, and to eliminate unnecessary detail.
An extensive survey of the surveillance data reported in Wales supports the assertion that there are substantial costs associated with MRSA infection, with a deleterious impact on healthcare outcomes on at least half of the patients found to be infected [ 15].
Some observers are wary of the significant hurdles to and substantial costs associated with building the NHII and do not support a large-scale effort to create a robust NHII.
A recent 2011 review of the economic burden of adult obesity in Europe confirmed substantial costs associated with care and reported preliminary subgroup analyses (eg, higher costs among severe obese individuals of higher economic standing) that may help guide future research and policy development.
Although many veterans are eligible for the GI Bill, which can cover substantial costs associated with law school, not all of them are eligible for full benefits.
