The phrase "a substantial contribution in" is correct and usable in written English.
It can be used when discussing the impact or importance of someone's input or effort in a particular area or field.
Example: "Her research made a substantial contribution in the field of renewable energy."
Alternatives: "a significant input in" or "a meaningful impact in".
Imaging biomarkers have a substantial contribution in detecting, localizing, and determining the extent of disease.
Its inclusion has a substantial contribution in satisfying the water requirement of the sheep.
Paragraph (5) permits reasonable compensation for an indenture trustee in making a substantial contribution in a reorganization or municipal debt adjustment case.
The club, however, insist that "the total value" of their contribution "comprising capital costs, direct funding, in kind, delivery and long-term public sector savings" is "a substantial contribution in excess of £20m".
As a result, the monitoring and assessment of forest biomass and carbon storage in China has managed to make a substantial contribution in this area.
Also, front and rear end collisions have a substantial contribution in automotive-related trauma and long term injuries than other types of road collisions as noted by Nishimura et al. (2015).
The findings, together with those of the In-Service Evaluation [ 10], could make a substantial contribution to improvements in pre-service and in-service midwifery education in Indonesia.
Although research in Africa has made a substantial contribution to progress in improving the delivery of effective interventions against communicable diseases such as HIV, tuberculosis and malaria, research on NCDs has lagged behind that on communicable diseases.
These results point to a substantial contribution of IRF6 in the etiology of non-syndromic CL/P in a sample of the Mexican population.
ClinPhen makes a substantial contribution to improvements in efficiency critically needed to meet the surging demand for clinical diagnostic sequencing.
Deployment of efficient, integrated energy systems can make a substantial contribution to reduction in greenhouse gas emissions.
