Sentence examples for a substantial constraint. from inspiring English sources

Nevertheless, the computational effort to run these models remains a substantial constraint on their application.

Four formidable, scalable organizations succeeding and capturing share in this marketplace is a substantial constraint to the growth of the traditional services providers.

It imposes, however, a substantial constraint: If we insist on including down markets in our comparison, we eliminate many of todays hot investment letters and mutual funds.

Defenders of Kant's ethics argue that it represents a substantial constraint: to avoid all those ways of thinking and acting that cannot be followed by all.

In many of these states health conditions are particularly difficult and the loss of skilled health workers is a substantial constraint to effective health care delivery.

This finding shows that form-selective motion sensitivity in the STS can be explained in terms of modulation of gain control on information flow in the motion pathway, and provides a substantial constraint for theories of the perception of faces and biological motion.

Again, we mostly see lower values, indicating a substantial selective constraint in terms of the breadth, too.

Furthermore, genetically modified mice are rather costly and may impose a substantial financial constraint to a research as well as limit the number of samples.

This indicates that the majority of methylation patterns in genome regions are not originated from stochastic methylation events but rather under substantial constraint.

a significant constraint.

While this definition is precise from a legal point of view, it causes substantial constraints as there are very few or no easy analytical methods to measure this variable without any conversions.