The phrase "a substantial breakdown" is correct and usable in written English.
It can be used to describe a significant failure or collapse in a system, process, or situation.
Example: "The project faced a substantial breakdown in communication, leading to missed deadlines and confusion among team members."
Alternatives: "a major failure" or "a significant collapse."
A federal appeals court, upholding the order last year, scorched the Department of Environmental Protection, citing "a substantial breakdown in the agency process that has resulted in 20 years of permanent cleanup inaction".
Credit for the scoop goes to Korea's Digital Daily which, among a substantial breakdown of the latest OLED shipment and yield rate data, reveals Google will source its new Pixel displays from LG.
In the event of a substantial breakdown of this nature, further support to the downside resides around the 1.2550 region, the level of the most recent price swing low.
Advanced progression leads to an increasing decay of the mineral structures, finally causing a substantial breakdown with related cavity formation.
In comparison with the United States, Germany has had a more substantial breakdown in output and has seen a much slower economic recovery, while the United States has faced a substantial rise in unemployment and a decline in employment.
At a later stage, the steadily increasing demineralization causes substantial breakdown of the microscopic mineral structures, which results in fluid pools within the surrounding almost intact mineral structures.
Lesions not visible using X-rays but visible by 3D UTE (CIII lesions) indicate very early lesions/demineralization with no substantial breakdown of the microscopic mineral structure.
Fulfill basic criteria of need for hospitalization for psychiatric treatment including insufficient general functioning and loss of mastery/function in multiple domains, e.g. inadequate self-care, substantial breakdown in relational, occupational, and/or personal functioning.
The reason for the superior tenderness of the fast pH group is suggested to be caused by a quicker and a more substantial proteolytic breakdown for this type of meat compared to the more slowly glycolysing muscles.
47 These findings indicated a substantial similarity of chlorophyll breakdown both in senescent leaves and in ripening fruit and suggested that the colour changes observed in ripening fruit and in senescent leaves were accompanied by a remarkably common biochemical path of chlorophyll breakdown.
Specifically, using a C-labelled anthocyanin and isotope-ratio mass spectrometry, we established that a substantial number and amount of breakdown products and conjugates of C3G were absorbed, metabolized and excreted; as represented by the recovery of 12% of the initial dose of C within the urine sample (Czank et al., 2013).
