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Following the work by Sørlie and colleagues that presented the intrinsic molecular subgroups of BC based on gene expression patterns, a substantial amount of information has elucidated the complexity in pathways driving the different BC subgroups.
A substantial amount of evidence has demonstrated that AS complexity is relevant to eukaryotic evolution, development, adaptation, and complexity.
A substantial amount of attention has focused recently on the complexity of the food safety system in the United States, which includes a huge number of agencies, sometimes overlapping programs, databases and legal authority, and the inevitable consequence of inefficient and confusing communication.
Not only is a substantial amount of energy is required for cooperation, the accompanied increase of complexity may be substantial as well.
#7 Nuance and Technical Complexity in Street Art Banksy's work is so often thought-provoking and/or requires a substantial amount of technical skill (outside of just being able to paint).
Gilder has done a substantial amount of both.
I have spent a substantial amount of money in development.
The foundation lost a substantial amount of money.
"He had a substantial amount of inflammation," Tellem said.
And noise complaints usually involve a substantial amount of subjectivity".
A substantial amount of their business is illegal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com