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The phrase "a substantial alignment between" is correct and usable in written English.
It can be used when discussing the degree of agreement or similarity between two or more entities, concepts, or ideas.
Example: "There is a substantial alignment between the company's goals and the employees' values, which fosters a positive work environment."
Alternatives: "a significant agreement between" or "a considerable correspondence between".
Exact(1)
Nevertheless, despite these differences, there is still a substantial alignment between the opinions of public funders and entrepreneurs.
Similar(59)
Nevertheless, although these differences were found, a substantial alignment of business angels and entrepreneurs in the perception of qualitative information may be pointed out.
Although these measures of pathway activation were expressed in different tissue, substantial alignment between gene expression in blood and brain biopsies has been shown in Parkinson's, Alzheimer's and Huntington's [ 48– 50] supporting the relevance of this profiling.
There is a strong alignment between the goals of the Born This Way Foundation and MacArthur's own.
There's a substantial difference between the two".
There is a substantial difference between the a.s.s
There is a substantial difference between the exit wave intensities.
(3) There is a substantial relationship between age and CRS.
Implementing the McMahon Act created a substantial rift between United States and Britain.
Is there a substantial difference between Romney's foreign policy and the Obama foreign policy?
There was a substantial overlap between the seven datasets.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com