The phrase "a substantial advantage over" is correct and usable in written English.
It can be used when comparing two entities, indicating that one has a significant benefit or superiority compared to the other.
Example: "The new software provides a substantial advantage over its competitors in terms of speed and efficiency."
Alternatives: "a significant edge over" or "a considerable benefit compared to".
Mr. Spitzer has also spent money courting black voters, among whom polls show him having a substantial advantage over Mr. Stringer.
A noteworthy characteristic of the Chinese system, and one that represented a substantial advantage over the Mediterranean systems, was its predilection for a decimal notation, as demonstrated by foot rulers from the 6th century bc.
Republican voters say Rudolph W. Giuliani has strong leadership qualities, and they associate him closely with his handling of the Sept. 11 terrorist attacks, but those impressions have not translated into a substantial advantage over his party's other presidential candidates when it comes to who can best fight terrorism, according to the latest New York Times/CBS News poll.
This range provides a substantial advantage over any other module available with WFT (2000 3000 psi in case of DP).
Samsung's renowned SSD technology offers a substantial advantage over the use of Hard Disk Drives (HDD) in a digital camcorder.
Cognitive scripts that enable codified knowledge to be transferred to a spin-off may grant the new firm a substantial advantage over the parent company.
On the basis of such a rapid growth of global biodiesel production during the first 15 years of the new millennium, the abundance of sources is undoubtedly a substantial advantage of biodiesel over conventional ester base fluids for drilling.
In modern mammals and birds, endothermy incurs an energy cost of maintaining a high basal metabolic rate, but provides a substantial advantage in aerobic capacity over ectothermic reptiles.
However, if such a signed form was not required, there was a substantial advantage to completing the interview over the phone (24% vs. 43%, p < 0.0001).
Taken together, these findings argue against a substantial advantage to measuring HMW adiponectin over, or in addition to, total adiponectin for assessment of glycometabolic risk.
This assay provides a substantial advantage in terms of scalability and quantification over solid-based media assays used previously to screen small libraries against other potassium channels.
