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Biomarker properties of a subset of discovered differentially methylated regions (DMRs) were validated using methylation-sensitive high-resolution melting (MS-HRM) in a case control study on a panel of breast carcinomas (n = 275) and non-malignant controls (n = 74).
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For example, some studies reported only a subset of the discovered genes, while others report functional analyses findings without actually listing the discovered genes.
The assay was developed from a subset of SNPs discovered using Perlegen hybridization technology and served to verify that most of the discovery-SNPs in the high quality MBML-intersect dataset [11] could be easily converted to assays based on single base extension.
A subset of the discovered SNPs was verified and genotyped in 36 commonly used strains (including BN).
To estimate the false positive rate of SNP discovery, a subset of the SNPs discovered by sequencing was genotyped in 1083 animals.
However, we randomly selected a subset of individuals, and we discovered no significant difference in patient demographics between responders and non-responders.
A targeted LC-SRM assay was developed to validate a subset of 13 candidate proteins discovered in the original 2D-DIGE non-targeted comprehensive survey.
We discovered a subset of red-shifted GRs that exhibit high levels of fluorescence relative to the WT (wild-type) protein.
We successfully discovered a subset of TFs that coordinately control cap growth and maturation.
Although M11 overlapped with M4, it discovered a subset of poor prognosis basal-like patients and it was prognostic of metastases recurrence within the basal-like breast cancer (P < 0.01).
They discovered a subset of cells that could be prospectively enriched in their cultures by fluorescence-activated cell sorting (FACS) for surface markers typically associated with normal stem cells, CD44 and CD24 (Al-Hajj et al, 2003).
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