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The initial gene discovery phase involves a genome-wide survey and, in the case of quantitative traits, is coupled to a subsequent validation of the most relevant candidate regions using near isogenic lines [ 4, 5].
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Double data entry was carried out with a subsequent validation to guarantee the quality and consistency of the data.
Either as an integral part of these techniques or as a subsequent validation step, the effect of deletions of the identified gene will be evaluated in animal or other laboratory models.
In a subsequent validation study, the tumours of a series of 295 consecutive women with breast cancer were used to validate the 70-gene prognostic profile (van de Vijver et al, 2002).
In a subsequent validation study, following re-administration of the screening questions, trained physiotherapists conducted a standardized examination of the hips and knees in 475 survey respondents (375 with and 100 without hip/knee complaints).
The systematic approach of sizing the power sources of a HOPS in terms of supply reliability using a statistical model and subsequent validation of the prediction with experimental data taking into consideration the cost of energy generated from the system is the unique feature of the present study.
The demonstration that Ees can be estimated in a single beat (EesSB) [ 12], and the subsequent validation of a noninvasive echocardiographic method to measure EesSB[ 13] through the measure of LVEF, SV, pre-ejection time and systolic time interval when coupled with systolic and diastolic arterial pressure, made the clinical bedside measure possible.
A two-phase prospective, observational study was conducted involving the development, and subsequent validation of a Mechanical and Inflammatory low back pain (MIL) index.
The objective of this study was to report the procedure followed for the cross-cultural adaptation and subsequent validation of a Spanish version of SPADI, including an examination of its psychometric properties.
Although imputation procedures were applied to fill data gaps to enable comparative analyses, the selection of an appropriate imputation method and subsequent validation of its application were challenging, especially because as much as 70% of the stage data was missing in some cases.
The aim of this study was to present an Arabic translation, adaptation, and the subsequent validation of the kidney disease quality of life-short form (KDQOL-SFTM) version 1.3 questionnaire in a representative series of Egyptian CKD patients.
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