The phrase "a subsequent refinement of" is correct and usable in written English.
It can be used when discussing improvements or adjustments made after an initial version or process.
Example: "The project underwent a subsequent refinement of its initial design to enhance functionality and user experience."
Alternatives: "an additional improvement of" or "a further enhancement of".
Structural modeling of nsSNPs was carried out using MODELLER [130], [131] with a subsequent refinement of side-chains by the SCRWL3 program [132].
In a subsequent refinement of the NS1 analysis, we separated sequences for this protein into two groups, corresponding to the two major NS variants known as Alleles A and B, whose nucleotide sequences exhibit approximately 70% identity [20], [21].
This interval of letting the mean gravity stabilize for 1 h with a subsequent refinement of the slower velocity is repeated until the end of the experiment.
Thus, a higher-level supervised separation of the high dimensional feature space into the rectangular shape hyperspaces is achieved via information-theory driven decision boundaries with a subsequent refinement of decision boundaries within the identified subspaces (see Step 2).
Although path lengths swum may be initially not significantly shorter than for the scanning or chaining, directed search is usually the beginning of a subsequent refinement in the efficiency of the search patterns applied to reach the goal platform from any possible start position.
Although path lengths swum may be initially not significantly shorter than for the scanning or chaining strategy directed search is usually the beginning of a subsequent refinement in the efficiency to reach the goal platform from each possible start position.
That would not exclude a subsequent refinement in, for example, further mechanisms of its regulation.
UC attorneys have argued that the move from prokaryotes to eukaryotes was obvious, and insisted that Zhang's lab's subsequent refinement of a key component in the CRISPR system a variation of an enzyme known as Cas9 also was obvious.
Subsequent refinement of a model with the oxime moiety pointing toward the side chain of Tyr341 resulted in a steric clash between the oxime and the tyrosine side chain.
This may or may not be correct, and is often based on their own or an acquaintance's previous experience of a problem, but it immediately directs subsequent refinement of the diagnosis.
The two main researchers shared this data set with the rest of the research team and discussions about the qualitative findings were a focus of three team research meetings which guided subsequent refinement of the analysis for this paper.
