Since copy-number changes are relative for array CGH data, unambiguous ascertainment of the ancestral state of a CNV and (subsequent) identification of duplications and deletions is challenging.
In the field of inverse metabolic engineering mapping of differences between strains with different degree of a certain desired phenotype and subsequent identification of factors conferring that phenotype are an essential part.
On the basis of the subsequent identification of a peak with significant prognostic value as a fragment of serum amyloid A (SAA), we have subsequently analysed total SAA as determined by ELISA and compared the clinical prognostic value of both total and C-terminal fragment of SAA pre-operatively, together with CRP.
The subsequent identification of an I304N Fmissenseense mutation in a severely affected FXS patient suggested that yet another class of FMR1 mutation was potentially a significant cause of disease [6].
With the subsequent identification of a complete Greek version contained in the medieval Christian legend of Barlaam and Josaphat, the reconstruction of Aristides' original text finally was achieved.
This study reports the positional cloning and subsequent identification of a candidate causative mutation.
Table 2 presents the t-values for the EMB comparisons at each lag. Figure 3 shows that while the EBM at Lags, 2, 4, and 6 reflects impairment in the subsequent identification of a neutral target, the EBM at lag 8 reflects significant enhancement of the subsequent identification of a neutral target.
Similarly, triple-immunofluorescence for HSA/twist/CD45 and HSA/vimentin/CD45 was performed with SK-Hep1 cells, a high-EMT HCC cell line (Supplementary Figure 2b), as a positive control for the subsequent identification of CTCs with twist and vimentin expression (Supplementary Figure 2c).
A larger number of health interventions assessed by cost-effectiveness analysis would in addition make the subsequent identification of an essential package of health interventions more credible.
The responses identified at a high concentration of EE2 were used to guide the subsequent identification of generally more subtle responses at a low concentration of estrogen.
