Sentence examples for a suboptimal option from inspiring English sources

Focal ablative therapy may be a suboptimal option for anterior prostate cancers (APCs) reaching the prostate apex due to concerns for thermal injury to the external sphincter.

TKA may represent a suboptimal option in terms of implant longevity in the former group and in terms of comorbidities in the latter.

Rats were then tested far beyond the indifferent point (i.e., 17%, 14%) when LLL became a suboptimal option and the economic benefit is attained unequivocally by choosing repeatedly the small-reward option.

On the contrary, the "gamblers" maintained a significant attraction for LLL, even beyond the indifferent point, when LLL became a suboptimal option (strategy × session: F 6,102) = 7.47, P < 0.001; Figure 2).

Such a strategy gains even more impetus since tumor suppressors such as DLC1 are generally not amenable to direct therapeutic targeting and blocking of Rho by geranylgeranyltransferase inhibition appears to be a suboptimal option due to the widespread cellular distribution of geranylgeranylation of proteins.

(EPA also provides a suboptimal "fast" option, which uses about 0.3 seconds/query after an initial setup time of 4 minutes or so for the entire set of queries).

These organisms can be resistant to all of the currently available antimicrobial agents or remain susceptible only to older, potentially more toxic agents, such as polymyxins, leaving limited and suboptimal options for treatment [ 2].

High levels of acute psychotic symptoms usually discourage clinicians and patient relatives and may lead to a suboptimal use of treatment options in severely ill patients.

For example, in accordance with local drug availability and regulatory requirements, fingolimod has been recommended as an option for treatment initiation and for patients with a suboptimal response [ 36].

This may represent an attractive option for patients with chronic phase CML that only achieve a suboptimal response or are resistant to TKI therapy, as well as for patients with advanced stage CML or Ph-positive acute lymphoblastic leukemia.

These prospective studies will better define the efficacy and safety of different treatment options, including escalated imatinib doses and treatment with nilotinib and dasatinib, in patients with a suboptimal response to imatinib.