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This result may be explained by the strain AUS-2001-4, whicoulduld not be firmly assigned to any of the two A subgroups.
aThe German sample constitutes a subgroups of the representative German sample surveyed with the BGS98.
Kaplan Meier analysis showed significantly different disease survival within the Luminal A subgroups (log-rank p = 0.015, Fig. S4).
We found that the CNH subgroup is consistently associated with a higher risk than the other Luminal A subgroups (Fig. S5), confirming the prediction of a worse prognosis.
Finally, we compared scores derived from research-based versions of Oncotype DX [ 1], Mammaprint [ 34], and PAM50 Risk of Recurrence (ROR-S) [ 8] across Luminal A subgroups.
The sample size limitations mostly reflect on the non-Luminal A subgroups, which are particularly under-represented among patients included in our analysis.
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No 17q25.3 gain was observed in the luminal A subgroup.
The main effect of rater was significant for the MCP joint in study part I-A and in all study part II-A subgroups.
The main effect of trial was significant for the MCP joint in imitated extension in study part I-A and in all study part II-A subgroups.
An examination of the expression data of clinical tumours and cell lines revealed higher activity in the enrichment score of microtubule/tubulin-related pathways for Stem-A than that for non-Stem-A subgroups (p = 6.6 × 10−67 and p = 2.1 × 10−6 by Mann–Whitney U-test, respectively; Fig 4; Supporting Information Table 16) (Verhaak et al, 2010).
A clear differentiation among all ABO-blood groups was achieved even for A-subgroups, with selectivity factor as high as four i.e. in case of blood group B typing.
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