The study calls for a concerted effort at addressing the structural, underlying causes and risk factors that lead to violence as well as improved availability of and access to culturally appropriate prevention, protection and response services.
Other inclusion criteria are; evidence of structural underlying heart disease, left ventricular ejection fraction ≤ 45% and age of at least 18 years.
These biophysical data reveal a structural basis that underlies, and can be used to predict de novo, broad genotype-phenotype correlations in HIF-2α-driven disease.
Addressing other features in need of clarification: A) While transverse breaks in the platinum along ESCRT-III filaments at ∼4 nm intervals are reproducible (and distinct from the 5.5 nm breaks seen along actin), they are a result of platinum decoration and may or may not directly correlate to a structural feature of the underlying filament.
The authors of this study seek to develop a causal and empirical computational model through a structural equation model and an underlying artificial neural network allowing for an argument outlining the psychological nature of the linkage between two interrelated constructs.
A variety of structural barriers underlie exclusion and must be identified and addressed if all Roma children are to get the best start in life and begin their educational careers on an equitable footing with their peers.
Our model of the TJ architecture provides a basis to discuss structural mechanisms underlying the selective ion permeability and barrier properties of TJs.
These breakpoints allowed us to delineate the structural rearrangement underlying a 5× copy number amplification of a ~11 kb genomic segment.
The structural properties underlie a procedure for extracting the global lattice from the direct product, which is the basis for a full-scale lattice construction algorithm implementing a divide-and-conquer strategy.
Potential bias and uncertainty may result from selective use of information, parameter precision, and structural assumptions underlying a model.
However, development of efficient small-molecule inhibitors has proven difficult, suggesting that a better understanding of the structural basis underlying phosphopeptide-SH2 domain interactions is required.
