The crystal structures have provided a structural framework to explore the mechanism of transport, which has sparked a large amount of biochemical, electrophysiological, mutagenesis and simulation studies on various members of the family.
In this work, we determined the solution structure by multidimensional NMR and provide a structural framework to elucidate its mechanism with computational simulation.
The observed structure reveals the mechanism of action of swinholide A and provides a structural framework about which to design new agents directed at the cytoskeleton.
Given the high homology between Kv1.2 and Kv1.4, including all relevant domains mentioned here, we use the structure of the former [3] and the Kvβ3 N-terminal as a structural framework of a N-type inactivation channel.
In other words, about one-third of the Freedom Tower will be more of a structural framework than a habitable building.
This work provides a structural framework in which to integrate previous physiology and pharmacology research and a rational basis for the development of GABAA receptor modulators.
In this paper, we develop a structural framework to facilitate the recovery of consumer preferences for game content and the optimization of firm content/price strategies.
Our results establish a structural framework for understanding how P. vivax reticulocyte-binding protein engages its receptor and the molecular mechanism of inhibitory monoclonal antibodies, providing important information for the design of novel vaccine candidates.
The papillae contain plates or ribbons of ciliated cells in a structural framework that lies on a movable membrane, except in amphibians, in which the papillae are on a solid base.
In an environment of fundamental changes, the authors provided a structural framework to apply to the analysis of the competitive scenarios, a starting point in developing corporate and business strategies.
In a statement issued after their meeting, the S.E.C. said, "As a first step, the parties agreed on a structural framework, to be refined over the next day, for strengthening circuit breakers and handling erroneous trades".
