The phrase "a structural alteration" is correct and usable in written English.
It can be used when referring to a change or modification in the structure of something, such as a building, system, or organization.
Example: "The city council approved a structural alteration to the historic building to improve its safety and accessibility."
Alternatives: "a structural change" or "a structural modification".
The electron microscopic examination of the basement membrane amniotic epithelium identified a structural alteration and edema of the dense lamina.
A mutant pRNA that had reduced procapsid binding was revealed to have a structural alteration within the procapsid-binding region that may account for the binding deficiency.
In 1949 American chemist Linus Pauling and colleagues demonstrated that a mutation causes a structural alteration in a protein; hemoglobin (the protein in red blood cells that carries oxygen to the tissues of the body) extracted from normal human red blood cells was shown to behave differently from hemoglobin taken from persons with the hereditary disease sickle-cell anemia.
One study shows a structural alteration of the wall of 58% of tracheotomy tubes after 30 days of use [94].
The goal of this study was to determine the precise molecular defect in a patient with ADA-deficient SCID whom we previously have shown to have a total absence of ADA mRNA and a structural alteration of the ADA gene.
It has been argued that although deamidation could be actually considered as a "structural alteration", at least in some instances, the persistence of such deamidation hot spots during evolution may otherwise serve to certain functions [5].
Hydrogen bonding interactions also contribute significantly to the binding energetics of biotin, and the D128A mutation which breaks a hydrogen bond between the protein and a ureido NH group results in a significant structural alteration that could mimic an intermediate on the dissociation pathway.
Long bones are severely bowed, and altered structure of the growth plates lead to a particular structural alteration of the metaphyses and epiphyses described a "popcorn appearance".
In vivo footprinting of the IRF-1 promoter: inducible occupation of a GAS element next to a persistent structural alteration of the DNA.
The introduction of a fluorescent dye together with a radiolabel (which is either covalently attached or complexed by a chelator system) can result in a significant structural alteration especially in case of rather small target-specific molecules.
Thus, the R210K mutation does not affect the oligomeric state of the construct nor significantly alter its overall shape, consistent with previous conclusions (27) that R210K causes a local structural alteration at the catalytic site, not a global folding defect.
