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The phrase "a strong replication" is correct and usable in written English
It can be used in contexts such as scientific research, experiments, or discussions about data validation where the quality of replication is being emphasized. Example: "The study provided a strong replication of the original findings, confirming the results across different populations."
Exact(3)
We have earlier shown that the overexpression of wild-type Twinkle in mouse heart promotes recombination junction formation together with an increase in mtDNA copy number [5] (Figure 4D), whereas the Twinkle dup352 364 mutation has been shown to impair helicase activity, resulting in a strong replication stalling phenotype in cultured cells as well as in mice [19].
Twenty-seven variants were validated in 285 cases and 355 controls from four breeds, resulting in a strong replication of the ADAM23 locus (praw = 2.76e 15) and the identification of a common 28 kb-risk haplotype in all four breeds.
At 2 h and 16 h post uptake in each cell type, the growth of the steC mutant was indistinguishable from that of the wild-type strain, while the ssaV mutant displayed a strong replication defect in both cell types (data not shown).
Similar(57)
Our study reports a strong replication-biased structuring of the Sulfolobus chromosome which implies that the multiple replication origins serve purposes other than only shortening the time required for replication.
Goat lung cells, alpaca kidney cells, and dromedary umbilical cord cells also showed strong replication, but virus did not replicate in sheep, cattle, rodent, or insectivore cells.
Whereas overexpression of wild-type Twinkle promote recombination of mouse heart mtDNA, mice carrying the Twinkle dup352 364 mutation show a strong mtDNA replication stalling phenotype, similar to the one observed in cultured cells expressing the same mutation [19].
Aphidicolin induces fork stalling like HU by inhibiting the activity of replicative DNA polymerases, while UV-induced lesions physically stall replicative DNA polymerases and induce both strong replication fork uncoupling and Chk1 phosphorylation (Byun et al, 2005).
The cellular results of the current study prompted us to investigate in vitro replication by three different DNA polymerases to determine if these lesions are strong replication blocks and if they are error-prone when a purified polymerase replicates past them.
Many other scientific fields without strong replication cultures may also be prompted now to embrace replications and reproducible research practices.
The Science paper shows that large-scale replication efforts of high quality are doable even in fields like psychology where there was no strong replication culture until recently.
We present an experiment that paired control and treated plots at 127 locations (with similar initial wood biomass, "twin-plot"), providing no experimental replication within sites, but strong replication within the population of stands across the landscape.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com