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The phrase "a strong difference in" is correct and usable in written English.
It can be used to describe a significant disparity or variation between two or more subjects or elements.
Example: "There is a strong difference in the performance of the two models, with one consistently outperforming the other."
Alternatives: "a significant difference in" or "a marked difference in".
Exact(45)
Third, these cells display a strong difference in vulnerability to different disease stimuli, the most prominent being cerebral ischemia [ 8- 11].
For example, if the structure of interest is small relative to the size of the rest of the structure (a gland within a whole larva, for example), then a strong difference in gene expression within the gland may be washed out by different patterns of expression elsewhere.
Such inequality in the critical exponent indicates a strong difference in the spatial structure of the percolation cluster, which results in the different slopes of the curves.
In 2001 Richard Nisbett and others wrote a widely read paper titled "Culture and systems of thought" that demonstrated a strong difference in thinking between the analytic West and the holistic East.
Vote Match hold weekly meetings where they discuss which new policies to add in – such as Labour's abolishing of the nom-dom rule – but in order to make the cut there has to be a strong difference in the parties' positions.
There was a strong difference in the effect across regions.
Similar(15)
This may be attributed to a stronger difference in preference between these foods (compared to the difference between yoghurt and red bell peppers), which may have motivated them to pay more attention to these foods' locations.
Age stratification revealed a stronger difference in WC with education in elderly men compared to younger men.
Considering that subjects were matched by platform type and other essential parameters, and also considering that previous authors found a stronger difference in deletion burden rather than duplication, the differences observed very likely translate to real biological differences.
Apparently, there is not any strong difference in the outcome.
A strong context can virtually override even a very strong difference in the preference for different meanings.
More suggestions(3)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com