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We have seen a strong decrease in the levels of H3K27me3 at the FLC locus in the absence of BRM.
However, combinations of either DOX or R with SLENU led to a strong decrease in the levels of MDA, compared to the levels when DOX and R were administrated alone (mean 0.569 μM and 0.543 μM, P < 0.0001); the levels of the former were close to those obtained from SLENU when administered alone.
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Strikingly, however, L50 tumours showed a strong decrease in the level of cyclin B1, as compared to HGT-1 tumours.
Had our method been dependent on the alignment score values, one could expect a strong decrease in the homology estimates as a function of the decrease in the identity level.
The inhibition of ODC caused a strong decrease in putrescine levels which might be a relevant event triggering cell cycle perturbations and apoptosis.
BSO is known to inhibit the first enzyme of the glutathione synthesis pathway thus leading to a strong decrease in glutathione levels [ 26- 31].
Consistent with the strong decrease in the level of 11-cis-retinal, Rpe65R91W/R91W mice suffer from S-opsin mislocalization at 1 month of age with a concomitant decrease in the number of S-opsin-positive cells with time [28].
In mice treated with rhDNase, a strong decrease in cf-DNA/NETs levels could be determined accompanied by a significant raise in the number of platelets.
As previously described for the unc-45 e286) unc-45 e286train13, we observed a strong decreastrain13osin protein levels in unc-45(m94) werms.
YFP RNAi resulted in a strong decrease in polyQ-YFP levels in Q40Bristol, and a weaker decrease in Q40DR1350.
In females, a strong decrease in E2 plasma levels was observed at 1 up to 100 µg/L, followed by recovery at 1000 µg/L.
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