Sentence examples for a strong alteration from inspiring English sources

We identified a strong alteration in regulation of genes related to iron homeostasis, including multiple cytochrome P450s, heme biogenesis and metabolism proteins, and others.

We recently reported that LRP-1 silencing severely impaired the invasion of malignant cells consecutively to a strong alteration of cell-matrix interaction turn-over.

However only two of the variants in the mature miRNA sequences exhibit a strong alteration in the in vitro functional assays that measure a subset of miRNA function; the in vitro function in two other variants with alterations in the pre-miRNA is also affected.

ARDS is clinically characterized by a strong alteration of ventilator mechanics with decreased lung compliance.

However, we note that all conditions with diminished p18 formation are characterized by a strong alteration in the p43-FLIP to p43/p41 ratio at the DISC.

We also observed Dohh depletion to cause a strong alteration of the transcriptional activity of more than 1000 genes in 3T3 cells.

We cannot rule out the possibility that migraine patients suffering from headache more frequently exhibit a stronger alteration of the autonomic nervous system, but then it becomes almost impossible to obtain interictal recordings.

Our general approach with a restrictive cut-off favors genes with either a consistent or a very strong alteration.

In this case, the hotspot results from the effects of a strong metabolic alteration and not directly from modification of a general regulator.

We used the gene for ARHGAP9 as a positive control for HP1β chromatin immunoprecipitation since this gene showed strong alteration in expression without showing evidence of altered expression subsequent to altered GRPR signaling, as determined by microarray, indicating that HP1β was likely binding in the vicinity of this gene.

For anomalies tilted towards the equator (τ= 90°), the flows show a strong azimuthal alteration along with the outer boundary heat flux.