The phrase "a stringent threshold for" is correct and usable in written English.
It can be used when discussing a strict or rigorous standard or limit that must be met in a particular context.
Example: "The organization has established a stringent threshold for data privacy compliance to protect user information."
Alternatives: "a strict standard for" or "a rigorous limit for".
Most GWAS analysis focused on individual SNPs have a stringent threshold for significance that must be applied due to the number of tests conducted in the study.
In order to minimize the mining of technical errors we defined a stringent threshold for alignment quality (expect≤1E-21) and the low quality ends of alignments were discarded.
This method of analysis yielded a relatively small number of peaks compared with other genome-scale ChIP studies [7], [39], [40], suggesting that by setting our parameters to define a stringent threshold for peak detection we may have increased the likelihood of false negatives.
A stringent threshold for co-expression identified two related calmodulin-like genes tightly associated with SID2.
In this study, we set a stringent threshold for female alignments of 30.
Applying a stringent threshold for the proportion of missing SNP genotypes, however, ensures detection and deletion of such animals in an earlier step.
To confirm that the binding sequence results were not dependent on the particulars of the thresholds chosen, we chose a stringent threshold of 10.6 for the enrichment scores as well as a more lenient value of 10.0 (Supplemental Figure 4).
Unexpectedly, our analyses reveal a stringent threshold of antigen persistence for both prophylactic and therapeutic treatments, although distinct mechanisms lead to tolerance in these two settings.
With a stringent threshold setting for the spectral count based semi-quantitation, the MudPIT experiment had nominated only two aaRSs candidates as androgen regulated.
While no SNP passed a stringent threshold required for genome-wide significance in the ALSPAC discovery set (0.05/315807=1.6 × 10−7), a number of SNPs in candidate genes displayed nominal associations with BMD, BMC, bone area and/or aBMC obtained from whole body DXA scans.
This pipeline compared signal tracks for the exponential growth condition to every other condition, one at a time, and called differential ends when the difference in signal between the two conditions exceeded a stringent threshold calculated for each gene based on internal signal noise (see Materials and Methods; Figure S4).
