Sentence examples for a stringent mapping from inspiring English sources
This fact creates significant potential for incorrect mapping of tags and means that much of the initial data generated becomes unusable when a stringent mapping methodology is utilised.
We therefore focused primarily on the subset of genes detected by all three technologies, through a stringent mapping of MPSS and SAGE tags to known genes, with a further limit to those also present in the oligoarray design.
While more stringent mapping quality filters can reduce these false-mapping rates, these filters would reduce the sensitivity of each of the other methods.
Sequences were grouped in clusters based on the following stringent mapping: any two sequences overlapping in their mapping against a given reference genome scaffold were put together into the same cluster.
It is noteworthy that due to the highly stringent mapping criteria applied in our previous studies [ 31, 32], a few mismatches in the alignments between the reference genomic sequence and the sequences generated from the Alu libraries were sufficient to lead to their classification as "partially mapped" reads.
Here, only those reads that (1) met stringent mapping criteria when mapped to the hg19 human reference genome (see Supplementary Methods), (2) were assigned to the Homo sapiens node in lowest common ancestor assignment by MALT, and (3) displayed typical ancient DNA damage profiles41 were included in a high confidence human dataset for further inspection.
Therefore, we took relatively stringent mapping conditions described above.
This success has been due to using highly stringent mapping parameters for subgenome-specific mapping.
High quality LG maps were then obtained in Carthagene using stringent mapping parameters.
We used stringent mapping parameters to minimize erroneous base calling and misaligned reads.
Test datasets were 1) all new genes based on stringent mapping criteria, 2) Type I New genes using stringent criteria, 3) Type II New genes based on stringent mapping criteria.
