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That is, if the question is whether or not there really is a "conservative reform" movement in policy, the answer would have to be no under a stringent definition of a movement.
Using a broad in silico screening based on a stringent definition of the RVxF motif, in combination with a multistep biochemical validation procedure, we have identified 78 novel mammalian PP1 interactors.
It is important to note that this high prevalence of abnormalities was found despite a stringent definition for an abnormal MRI.
The use of a stringent definition of a positive result was implemented in this study in order to maintain high specificity [13].
Thanks to a stringent definition of functional characterization this approach allows the generation of a large set of high-confidence predictions in terms of functional annotation and the identification of new candidate disease genes.
Validated assays, with a stringent definition of a true positive signal, are therefore essential.
Similar(28)
For example, studies using a broader definition for a Campylobacter case would result in higher case numbers and a lower proportion for the sequela estimate versus a study with a more stringent definition for a Campylobacter case.
By a less stringent definition, using a reticulocyte cut-off of less then 150,000/uL (∼3% of erythrocytes in a non anaemic child [18]), 86% of all severely anaemic children fell into the RCPF category (table 1).
The value of 30 nt for RS and RT was chosen empirically, observing the normal range of variation in the start and end positions of transcripts, and looking for a tradeoff between a more stringent definition of the isoform structures and the requirement to recognize similar isoforms.
Previous work has used a rather stringent definition of a small geographic area: when it has no unique individuals on the potentially identifying variables (quasi-identifiers).
Even when a relatively stringent definition of a clonal group (<3-band difference) was used, >80% of human MDR isolates composed 2 clonal groups.
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CEO of Professional Science Editing for Scientists @ prosciediting.com