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In an effort to reduce the complexity of the interactions contained in the network modules we constructed consensus networks based on the most abundant HLA proteins for each risk group and only included partners outside the HLA with a stringent criteria (see Methods).
To further improve the robustness, we applied a stringent criteria (median FPKM across multiple human ES samples > 1) when calling hES lincRNAs.
Although this filtering provides a stringent criteria for detecting differential late gene expression, we were still left with 4456 potential genes that are candidates for late-onset differential expression.
This is a stringent criteria and might miss some genes, in particular those on a trisomic t(X A) where only one of the three copies of an autosomal gene subject to inactivation is expected to gain DNAm.
As we pointed out in our previous work [ 2], some known POU5F1 target genes were missed in the POU5F1-target gene list assembled by Loh et al. [ 1] partly due to the use of a stringent criteria (i.e., ≥ 4 ditags).
Comparisons with the predicted proteome of M. anisopliae E6 and the PHI-database were conducted employing Blastp analysis and the results were filtered according a stringent criteria (coverage ≥ 50% and e-value ≤ 10-5).
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The paper follows a stringent criterion by considering only individuals who claim to be able to speak Spanish "very well".
Plainly, the doctrine presupposes a stringent criterion for knowledge, at least as demanding as the test for techne.
In order to reduce the possibility of false discovery, we adopted a stringent criterion wherein we considered only those genes as differentially expressed, which were selected by both the algorithms.
It has been acknowledged that the availability of (public) recharge infrastructure will be a stringent criterion for many vehicle purchasers – also if public infrastructure will only serve as reassuring secondary recharging option for most vehicle users.
A stringent criterion (q<0.05 and fold changes >2) was used to identify transcripts whose expression levels were significantly changed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com