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In HaCaT cells, silencing of endogenous YAP resulted in a striking decrease in the levels of endogenous ΔNp63 α.
Removal of either CRX, RAX or NEUROD resulted in a marked decrease in blue opsin, S-antigen, PDE6C and CNGB3 levels; withdrawal of RAX resulted in a marked decrease in expression of blue opsin, and withdrawal of NEUROD resulted in a striking decrease in expression of PDE6C.
We also observed a striking decrease in the expression of β-casein (Csn2), a marker of mammary epithelial differentiation.
In addition, at several axon terminals there was a striking decrease in the number of synaptic vesicles.
More detailed analysis revealed a striking decrease in spine density of CA1 pyramidal neuron apical dendrites (Fig 4B and D).
We observed a striking decrease in the serum creatine kinase (CK) levels in AT rats (371±223 U/L), compared to AC rats (737±178 U/L).
However, when we examined the levels of IFNAR1 expression in the groups, we saw a striking decrease in the receptor expression on CD103+ DCs in the PPs of mice treated with La-IFN-β (Figure 5E).
A striking decrease in square-law slope upon addition of cholesterol denotes stiffening relative to the pure lipid bilayers that is diminished in the case of lanosterol.
AI therapy is designed to result in a striking decrease in estrogen synthesis and in decreased circulating estrogen levels [ 6].
Compared with that of Study 1, a striking decrease in the dissimilarity for experiments on the same spectrometer was observed.
Western blotting showed that knockdown of LRP6 led to a striking decrease in β-catenin protein.
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