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Long bones develop through a strict coordinated process of endochondral ossification within the growth plate resulting in the replacement of cartilage by bone and defect in this coordinated process may result in skeletal abnormalities such as dwarfism, kyposis and also age-related defects such as osteoarthritis (OA).
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This finding is most surprising as it seems to violate common biochemical wisdom that 'The activities of the pathways that produce ATP are under strict coordinated control so that ATP is never produced more rapidly than necessary' (quoted from [ 31]).
He was a strict disciplinarian.
Isn't a strict Muslim?
Jose Bautista is a strict constructionist.
This is a strict drag.
It's a strict sensation.
The solution is a strict diet.
There is a strict code of confidentiality.
It was a strict business transaction.
She is a strict Jehovah's Witness.
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