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The phrase "a straightforward comparison between" is correct and usable in written English.
You can use it when discussing or analyzing two or more items, concepts, or ideas in a clear and direct manner.
Example: "In this report, we will provide a straightforward comparison between the two marketing strategies to determine which is more effective."
Alternatives: "a clear comparison of" or "an uncomplicated comparison between".
Exact(15)
On a general note, the different scaling of length, surface area and volume makes a straightforward comparison between microchannel reactors and conventional reactors far from trivial.
From a straightforward comparison between parallel- and perpendicular-direction hysteresis loops, we can deduce that the easy magnetization direction is parallel to the NW/NT long axis, and the perpendicular direction is a magnetization hard direction.
Therefore, while such corrections should be taken into account for a rigorous calculation, we expect that the LF effects will have the same influence on Si and Ge NCs of the same size and geometry, allowing in principle a straightforward comparison between the responses of the two compounds.
She did not make a straightforward comparison between "a Latina woman" with "a white male".
This facilitated a straightforward comparison between studies.
A study providing a straightforward comparison between chemotherapy and/or radiotherapy and SEMS is lacking.
Similar(44)
Cetuximab is modeled as a monovalent binder of EGFR to focus on a more straightforward comparison between drugs that compete with single ligand or ATP binding events in the extracellular or intracellular compartments, respectively, but the slightly enhanced binding affinity observed for the bivalent full-length antibody was used in model parameterization.
Unlike previous transcriptomes in the field of symbiotic cnidarian biology, these data are derived from a clonal and easily distributed strain of anemone, greatly facilitating a straightforward comparison of experimental results between different laboratories.
Perhaps such a straightforward comparison is an ill-conceived goal; arguably, numbers may not be translated between species but behaviors likely can.
Unlike other indices, Halifax bases this figure on a comparison of quarterly averages, and a straightforward comparison of average prices in March 2013 and March 2014 showed a rise of 8.4%.
Therefore, again, a straightforward comparison with the works cited above are not meaningful.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com