The phrase "a stepwise trial" is correct and usable in written English.
It can be used in contexts related to research, experiments, or processes that are conducted in a sequential or incremental manner.
Example: "The researchers conducted a stepwise trial to evaluate the effectiveness of the new drug over several phases."
Alternatives: "incremental trial" or "sequential trial".
After stabilization of the lung injury model (> 1 hour) a stepwise PEEP trial was performed consisting of 2-minute steps of tidal ventilation (10 30 cmH2O; 30–5 cmH2O).
After stabilisation of the lung injury model (> 1 hour) a stepwise PEEP trial with 2 min at each pressure ramp was performed (10 up to 30 mbar and 30 down to 5 mbar) with an electrically controllable ventilator (Servo 300; Siemens-Elema).
In the STEPwise trial, insulin aspart was added to either the largest meal (SimpleSTEP) or to the meal with largest prandial glucose increments (ExtraSTEP).
The effect of a stepwise ascending and descending PEEP trial on alveolar recruitment/derecruitment in porcine saline-lavage-induced lung injury could be displayed in EIT analysis and may directly be helpful in titration of PEEP.
All vaccines under development follow a predefined pathway that begins with nonclinical testing (in suitable animal models and in vitro testing), followed by a stepwise evaluation in human clinical trials to demonstrate safety and efficacy.
Non-inferiority is often tested first, but both non-inferiority and superiority can be evaluated in the same trial typically in a stepwise, or hierarchical, manner.
7 The development of a new medicine requires the successful completion of a stepwise process involving a number of trials.
A simple dressing consisting of blue gauze and Tegaderm was used in a preliminary clinical trial as part of a stepwise introduction.
It is now suggested that newer drugs to be tested for advanced HCC should go through all phases in a stepwise fashion before beginning a Phase III trial.
In a press release, the EMA reinforced its commitment "to push ahead in 2014 toward publication and access to clinical trial data", but announced a stepwise approach and implementation to be developed in the first half of 2014 (EMA Press Office, 2013).
