In other words, if we knew the selenium metabolism rates for individual trial participants, especially the rates of methylselenol production and selenium transport, we might be much more confident about the probability of obtaining a statistically significant beneficial trial outcome.
This awareness translated into a statistically significant increase in trial registrations for RCTs with patient recruitment after 2005 in urology and better registration of trials in other medical specialties.
Scores on all other domains were either not statistically significantly different between the two samples or showed a statistically significant advantage for trial patients.
Even though the conventional meta-analyses of non-fatal myocardial infarction, composite microvascular complications, and retinopathy indicated a statistically significant effect estimate, trial sequential analysis showed that sufficient evidence was not yet available for a conclusion to be reached.
Even though the conventional meta-analyses of composite macrovascular complications, nephropathy and severe hypoglycaemia indicated a statistically significant effect estimate, trial sequential analysis showed that sufficient evidence to detect or reject a 10% relative risk reduction or risk increase was not available for any of these outcomes.
All effector systems show that those who habituate on trial 2 show a statistically significant greater response on trial 1 than those who sensitize from trial 1 to an identical stimulus.
Subjects attempt to guess correctly the symbols of cards hidden from their view under controlled conditions; a better-than-chance percentage of correct calls on a statistically significant number of trials is considered to be evidence of ESP.
The combined meta-analysis did not find a statistically significant effect (two trials, 558 participants, Analysis 5.1).
Similarly, Dr Phillip Dellinger emphasized that although anti-tumor-necrosis-factor therapy has not shown a statistically significant benefit in trials and meta-analysis, the signal of benefit might be increased by careful patient selection.
In this trial, a statistically significant impact on math test scores was found by intention to treat analysis among Chinese children randomized to receive free glasses, although this difference between groups was smaller than the prespecified difference that the study was powered to detect.
It did not prolong patients' lives by a statistically significant amount, though the trial was too small to have detected such an effect unless it were huge.
