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The phrase "a statistically significant mitigation" is correct and usable in written English.
It can be used in contexts related to research, statistics, or discussions about the effectiveness of interventions or treatments.
Example: "The study found a statistically significant mitigation of symptoms in patients who received the new therapy compared to those who did not."
Alternatives: "a meaningful reduction" or "a notable decrease".
Exact(1)
Linear regression plots indicate that coexposure to as-produced CB nanoparticles or PAC induced a dose-dependent decrease in mortality, but only PAC caused a statistically significant mitigation when compared to 200 mg/L benzene.
Similar(59)
Balogh et al. [ 37] found that bathing in mineral water resulted in a statistically significant improvement of pain, mitigation of muscle spasm, alleviation of local tenderness, enhanced flexion-extension and rotation of the spine, which persisted as long as 3 months after the completion of balneotherapy.
Another important finding was the lack of a statistically significant relationship between perceived risks to agriculture (e.g., "potential impacts on my farm operation") and support for mitigation.
Nonetheless, a statistically significant link was shown.
That is a statistically significant difference.
Eight diseases have a statistically significant module in liver tissue.
P < 0.05 was considered to indicate a statistically significant difference.
That's a statistically significant difference of 22 percentage points.
The symbol '#' indicates a statistically significant difference with P < 0.05.
Logistic regression resulted in a statistically significant model (p < 0.001).
It appears to be a statistically significant move, not one caused by mere chance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com