The phrase "a statistically significant decrease in expression" is correct and usable in written English.
It can be used in contexts related to research, statistics, or scientific studies when discussing the results of an experiment or analysis that shows a meaningful reduction in expression levels.
Example: "The results indicated a statistically significant decrease in expression of the target gene after treatment."
Alternatives: "a meaningful reduction in expression" or "a notable decline in expression."
In summary, leukemia-derived cell lines and bone marrow cells from patients with leukemia show a statistically significant decrease in the expression of WNT4 when compared with the expression in PBMCs from healthy individuals.
There was a statistically significant decrease in cytokine expression of IL-4 (p = 0.05) and a significant increase in cytokine expression of IFN-γ (p = 0.01), IL-10 (p = 0.03), IL-12p70 (p = 0.02), and IL-7 (p = 0.0001) in RRG compared to CG (Fig. 3a).
However, the test compounds caused a statistically significant decrease in the expression of the anti-apoptotic protein Mcl-1.
We found a statistically significant decrease in the expression levels of the PHD1, PHD2 and PHD3 genes in cancerous tissue compared to histopathologically unchanged colorectal tissue.
Caspase-7-deficient Caspase-7-deficient Caspase-7-deficient Caspase-7-deficient in the expression of mandibular change: −2.17; P=0.0058) and Smad1 (fold change: −2.2; P=0.0147) in early development (ED15.5).
Five of these downregulated genes showed a statistically significant decrease in their expression levels (p< 0.05): PSA, NDRG1, FGF8, CDK1, and PMEPA1.
MDA-MB-231 cells were treated with varying doses of curcumin and at 30 μM of curcumin, a statistically significant decrease in PPARβ/δ protein expression level was observed, concomitant to the decrease of FABP5 expression by curcumin.
Elevated dSir2 expression led to a statistically significant decrease in lacZ-expressing cells by day 20 in oenocytes (Fig. 6).
Both the oligodendromas and astrocytomas showed a statistically significant decrease in REST target gene expression with respect to their non-neoplastic counterparts.
Interestingly, IFN-α-neutralizing antibody reduced STAT1 activation (48% inhibition) and significantly reduced TRAIL expression levels, whereas IFN-β-neutralizing antibody treatment did not cause a statistically significant decrease in STAT1 activation or TRAIL expression (Fig. 6I, J).
