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Path dependence refers to a success-driven process that may lead organizations into a state of persistence in which they continuously reproduce a strategic pattern (Sydow et al. 2009; Vergne and Durand 2010).
Through an evaluation of the relative balance between institutional continuity and change, social-ecological systems may be typified in a state of persistence (continuity > change), adaptation (continuity ~ change) or transformation (continuity < change) (Herrfahrdt-Pahle and Pahl-wostl 2012).
Surviving bacteria are believed to enter a state of persistence [2] which can be lifelong.
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AhpC is up-regulated during transition of mycobacteria to a state of chronic persistence [55] and is involved in oxidative stress defence within host macrophages.
At the onset of adaptive immunity, activated macrophages keep the infection under control, but the bacteria are not eliminated, and a state of chronic persistence is established [ 36].
This finding suggests that pigs were probably in a state of reinfection or persistence of antigenic stimulation of the agent.
LTBI is caused by tubercle bacilli in a state of non-replicating persistence (NRP), and the goal of this study was to evaluate the activity in vitro of various antimicrobial agents against non-replicating M. tuberculosis.
Aerosolized Mtb, once inhaled into the lung and internalized by alveolar macrophages can induce phagocyte activation leading to control of bacillary growth and establishment of a state of non-replicating persistence [ 1- 3].
Previous studies showed that prolonged exposure to antibiotics activated transcription of TAs encoding mRNases in E. coli K-12; this activation led to inhibition of global cellular translation, rendering the cells to a state of dormancy and persistence.
In addition, presence of histological signs suggestive of persistence of a state of the activated BALT, even in less aggressive sepsis (S8-30d), shows that still exist a continuous stimulating inflammatory factor even in the absence of clinical signs of infection.
But more than anything the centre is a state of mind in which stability and persistence matter more than dogma.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com