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This serves as a starting point for validation and optimization in the discovery of new p53-MDM2 antagonists.
However, reproducing one particular outbreak should be just a starting point for a validation strategy.
The list of putative protein targets is a starting point for experimental validation by in vitro assays and further discovery of new drugs in order to treat the sperm-egg interaction defect.
As a starting point for further validation of FDG-PET in multi-centre studies and meta-analyses, Wahl et al. [ 54] have proposed guidelines for the standardisation of response criteria for FDG-PET, the so-called PET Response Criteria in Solid Tumours (PERCIST).
An initial condition of a medium site quality Chinese fir plantation age 20 was established as a starting condition for the model validation exercise.
Given its performance on the single knockdown prediction task, the ranked list of pairs identified by SDREM can serve as a starting point for follow-up validation experiments.
The critical amino acid residues for functional divergence identified here provide new insights into the functional evolution and diversification of UCP genes, and since knowledge on UCP function is limited especially in fishes, they offer a starting point for further experimental validations.
Although these 'gene-trait relationships' need extensive analyses using other NU varieties or a rice diversity panel, the graphical genotype we have presented can be a starting point and also guides functional validation by molecular genetics.
The presented findings will serve as a starting point for the third phase: validation of the data.
Issues are relatively minor: What was the rationale for a starting concentration of 1μg/ml for initial validations?
I note that the stromal staining was still present at selected concentration of 0.5μg/ml (dataset f) What was the rationale for a starting concentration of 1μg/ml for initial validations?
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