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These are calculated setting a mean of 100 and a standardised deviation of 7 units.
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In the present study, the durations of all subjects between the time points of performing the HADS and blood sampling had a mean value of 3.6 days and standardised deviation of 5.0 days, and those of 95% of all subjects were under 15 days.
This could be explained by higher mean values and bigger standardised deviation of the simulated LNG prices at Japan.
In order to detect a standardised difference of 0.5 standard deviation in the primary outcome measure (which can be considered as a clinically relevant difference), 2 × 63 patients are needed when two-sided testing and 80% power is assumed.
The difference found between the groups is equal to a standardised mean difference of −0.30 (−0.54 to −0.07), with baseline standard deviation for SCL-D13 (pooled).
The mean, median, standardised deviation, and range of duration between the time points of performing the HADS and blood sampling of all subjects were 3.6, 2.0, 5.0, and 0 33 days, respectively.
Blinded assessors determined in a standardised fashion the deviation of the puncture off midline and whether appropriate longitudinal position between the first and fourth tracheal rings was achieved.
Abbreviations: Standardised deviation (SD), Close Persons Questionnaire (CPQ), Patient Health Questionnaire PHQQ).
This bias translates to a standardised effect size of 0.4 (0.4 of the baseline standard deviation).
A previous small study using a similar intervention found a mean benefit of 0.7 in the AIMS2 with a standard deviation of 1.81 and a standardised effect size of 0.39 [ 36].
The average EBV for the lipid content of the Fat families was 2.00 percentage units higher than that of the Lean families, representing a standardised selection differential of 2.33 standard deviations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com