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Goce's slender, fin-shaped construction, combined with its magnetic attitude-control system, maintained a stable orientation until very late in the descent.
A recent cryo-electron microscopy (EM) analysis revealed that pol II adopted a stable orientation within a Mediator pol II TFIIF assembly in which Mediator was bound to the activation domain of viral protein 16 (VP16).
Detailed analysis of the mechanics of crystal rotation shows that the orientations belonging to the sets 〈1 1 0〉//TD and 〈1 1 1〉//TD can rotate between two unstable orientations before a stable orientation is reached.
Moreover, the loop was found in a stable orientation only for ternary complexes, which had enzyme, cofactor and steroidal product or inhibitor fully resolved (1a27, 1fdtA, 1fdtB, 1equA, 1fduC and 3hb5; cluster cl2 in Figure 3).
(iii) Ad hoc folding of a secondary structure is unlikely to produce a stable orientation of hydrophobic and hydrophilic residues.
On the other hand, when the leading head detaches from actin, the molecule would not take a backward step because the trailing head is bound to actin in a stable orientation (i.e., the forward leaning orientation).
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At the end of this period (about 50 ns), DNA adopts a relatively stable orientation with the major groove facing the TRD and the minor groove facing the catalytic loop).
Validation by SUPERPOSE and with the use of PROCHECK program showed folding of 98% of modeled residues in a favourable and stable orientation with a total energy Z-score of −6.56; the constructed model has an RMSD of only 1.15 Å.
More recently, Chakrabarty and coworkers [ 255] individually tested the accuracies of EM, NSM, and PM in predicting three-dimensional D f of two-dimensional aggregate images by applying them to a statistically significant (~2500) number of projected images of all stable orientations of computer-generated three-dimensional fractal aggregates with D f ranging between 1.0 and 3.0.
By doing this, it seems better placed to foster the consistency among different kinds of normative elements and to bound action to a stable normative orientation, yet open and flexible.
The illusion of a stably sexed body, core gender identity, and (hetero) sexual orientation is perpetuated through repeated, stylized bodily performances that are performative in the sense that they are productive of the fiction of a stable identity, orientation, and sexed body as prior to the gendered behavior (173).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com