Sentence examples for a stable modification from inspiring English sources

It represents a stable modification of DNA that can be propagated during cell division, yet is susceptible to environmental influence.

In order to determine which modified tyrosine residues could be responsible for the inhibition of the D-form, a stable modification was a prerequisite.

Soon after its identification, histone methylation was thought to be a stable modification, as no enzymes were known to remove this mark.

This further supports the notion that H3-K27me3 is a stable modification in Drosophila that is apparently not subject to constant turnover.

A role of 5hmC as active mark is supported by mass spectrometric analyses of isotope labelled DNA form mammalian cell culture and mice showing that 5hmC is mostly a stable modification and not a transient intermediate [ 67].

DNA methylation, a stable modification that is often provoked by RAS, controls the expression of a number of genes through epigenetic mechanisms that recruit different transcriptional repressors in an orderly fashion.

DNA hypermethylation is a relatively stable modification and has therefore been investigated as a potential biomarker, as reviewed in Phé et al. (2010).

DNA methylation is thought to be a highly stable modification that helps maintain intergenic and heterochromatic regions in a transcriptionally inert chromatin state (Bird, 2002; Klose and Bird, 2006).

H3K27me3 is a rather stable modification, which could be progressively lost in the absence of PRC2, along with cell divisions [39].

Histone methylation is a very stable modification compared with, for example, acetylation.

DNA methylation has traditionally been considered to be a mitotically stable modification that could change only over long periods of time, e.g., in disease development and during the general aging process.